Steven A. Sandler, M.D.
Board-Certified in
Hematology & Oncology
Telephone Numbers
Office: (847) 933-0875
Fax: (847) 933-0878
Answering Service: (773) 594-7340
Skokie Office
9669 Kenton, Suite 510
Skokie, IL 60076
Map and directions
Chicago Office
7447 W. Talcott Ave., Suite 318
Chicago, IL 60631
Map and directions
Call us at 847-933-0875 or send Dr. Sandler a message via the form below. Please note that this form is for non-emergencies only.
Splenomegaly / Enlarged Spleen and Treatment
About Splenomegaly / Enlarged Spleen
Splenomegaly is an enlargement of the spleen, which lies in the left upper quadrant (LUQ) of the human abdomen. The spleen is part of the lymphatic system and works as a drainage network in the body, helping to filter out toxins and defend the body against infection. Splenomegaly is usually associated with an increased workload such as in hemolytic anemia. An enlarged spleen can also be caused by infections, cirrhosis and other liver diseases, blood diseases characterized by abnormal blood cells, Gaucher’s disease, or other conditions. Splenomegaly is associated with any disease process that involves abnormal red blood cells being destroyed in the spleen.
Signs and symptoms of spleenomegaly / enlarged spleen may include:
- Being unable to eat a large meal
- Feeling discomfort, fullness, or pain on the upper left side of the abdomen, which may spread to the left shoulder
- Fatigue
- Weight loss
- Easy bruising
- Anemia
Splenomegaly / Enlarged Spleen Treatment
The treatment of splenomegaly depends on the underlying cause of the diagnosis but needs to be treated immediately as serious complications can result from an enlarged spleen. Depending on the severity of the condition, surgery is sometimes necessary to remove the spleen (splenectomy). It is recommended to limit or avoid any activities that could rupture the spleen, such as contact sports.
