Steven A. Sandler, M.D.
Board-Certified in
Hematology & Oncology

Telephone Numbers
Office: (847) 933-0875
Fax: (847) 933-0878
Answering Service: (773) 594-7340

Skokie Office
9669 Kenton, Suite 510
Skokie, IL 60076
Map and directions

Chicago Office
7447 W. Talcott Ave., Suite 318
Chicago, IL 60631
Map and directions

Call us at 847-933-0875 or send Dr. Sandler a message via the form below. Please note that this form is for non-emergencies only.

Mastocytosis and Treatment

About Mastocytosis

Mastocytosis is a group of rare disorders of both children and adults caused by the presence of too many mast cells (mastocytes) and CD34+ mast cell precursors in a person's body. Mast cells play an important role in wound healing and are an integral part of the body’s immune system (the body’s defense against illness and disease). There are two main types of mastocytosis: cutaneous (confined to the skin only) and systemic (includes the organs and skin). Cutaneous mastocytosis is much more common than the more serious systemic mastocytosis, which can affect the liver, spleen, lymph nodes, and bone marrow. Because mast cells play a role in allergic reactions the symptoms of mastocytosis are often similar to symptoms of allergic reactions.

Mastocytosis signs and symptoms may include:

• Fatigue
• Skin lesions and itching
• Nausea, vomiting, and abdominal pain
• Food and drug intolerance
• Infection(bronchitis, rhinitis, and conjunctivitis)
• Ear, nose, and throat inflammation
• Bone and muscle pain
• Episodes of very low blood pressure and fainting

Mastocytosis Treatment

The treatment of mastocytosis usually involves medications.  The diagnosis is usually uncomplicated.  Most patients have a rash and abnormal bone marrow. While this uncommon disorder is easily treated, it is sometimes difficult to diagnose.  Sandler Cancer Treatment Centers provide treatment for people with mastocytosis.