Steven A. Sandler, M.D.
Board-Certified in
Hematology & Oncology

Telephone Numbers
Office: (847) 933-0875
Fax: (847) 933-0878
Answering Service: (773) 594-7340

Skokie Office
9669 Kenton, Suite 510
Skokie, IL 60076
Map and directions

Chicago Office
7447 W. Talcott Ave., Suite 318
Chicago, IL 60631
Map and directions

Call us at 847-933-0875 or send Dr. Sandler a message via the form below. Please note that this form is for non-emergencies only.

Monoclonal Gammopathies (MGUS) and Treatment

About Monoclonal Gammopathies

Monoclonal gammopathy of undetermined significance (also referred to as MGUS or paraproteinemia) is a condition in which abnormal proteins are found in the blood. In most people it doesn’t cause any significant problems and is benign (non-cancerous). In some people, MGUS may progress to more serious conditions, including some forms of cancer. Because it isn’t possible to predict who will develop complications or cancer, people with MGUS must be monitored closely and have regular blood tests to check protein levels.

Signs and symptoms are very rare. MGUS is usually detected when getting a blood test for another reason.

Treatment for Monoclonal Gammopathies

It is important to accurately diagnose MGUS and make sure there is no other disease associated with this disorder.  If it is a benign (non-cancerous) monoclonal gammopathy, then no treatment is necessary but careful monitoring and regular blood tests will be conducted.  While most patients do well, occasionally patients need treatment for a progressive disease resulting from MGUS.